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Insm1 controls development of pituitary endocrine cells and requires a SNAG domain for function and for recruitment of histone-modifying factors.
Welcker JE, Hernandez-Miranda LR, Paul FE, Jia S, Ivanov A, Selbach M, Birchmeier C. Welcker JE, et al. Development. 2013 Dec;140(24):4947-58. doi: 10.1242/dev.097642. Epub 2013 Nov 13. Development. 2013. PMID: 24227653
We show here that Insm1 is required for differentiation of all endocrine cells in the pituitary. ...Our work demonstrates that Insm1 acts in the epigenetic and transcriptional network that controls differentiation of endocrine cells in the anterior pituita …
We show here that Insm1 is required for differentiation of all endocrine cells in the pituitary. ...Our work demonstrates that …
Analysis of Insulinoma-Associated Protein 1 Expression in Pituitary Neuroendocrine Tumors.
Hirokawa Y, Inomoto C, Oyama K, Tahara S, Y Osamura R, Shiomi T, Matsuno A. Hirokawa Y, et al. Acta Histochem Cytochem. 2023 Dec 28;56(6):105-110. doi: 10.1267/ahc.23-00033. Epub 2023 Dec 20. Acta Histochem Cytochem. 2023. PMID: 38318099 Free PMC article.
INSM1 expression in PitNETs (different subtypes) and normal pituitary tissues was immunohistochemically assessed. ...INSM1 expression in most PitNETs was obtained, similar to that in the normal pituitary gland; thus, INSM1 may maintain th …
INSM1 expression in PitNETs (different subtypes) and normal pituitary tissues was immunohistochemically assessed. ...INSM1 …
Olfactory neuroblastoma (esthesioneuroblastoma) presenting as ectopic ACTH syndrome: always follow your nose.
Decaestecker K, Wijtvliet V, Coremans P, Van Doninck N. Decaestecker K, et al. Endocrinol Diabetes Metab Case Rep. 2019 Oct 17;2019:EDM190093. doi: 10.1530/EDM-19-0093. Online ahead of print. Endocrinol Diabetes Metab Case Rep. 2019. PMID: 31627184 Free article.
Further testing, including 24-hour urine analysis, late-night saliva and low-dose dexamethasone suppression test, confirmed hypercortisolism. An MRI of the pituitary gland was normal. Inferior petrosal sinus sampling (IPSS) revealed inconsistent results, with a rais …
Further testing, including 24-hour urine analysis, late-night saliva and low-dose dexamethasone suppression test, confirmed hypercortisolism …